Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

Malaria-protective CD8+ T cells specific for the circumsporozoite (CS) protein are primed by dendritic cells (DCs) after sporozoite injection by infected mosquitoes. The primed cells then eliminate parasite liver stages after recognizing the CS epitopes presented by hepatocytes. To define the in viv...

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Detalles Bibliográficos
Autores principales: Cockburn, Ian A., Tse, Sze-Wah, Radtke, Andrea J., Srinivasan, Prakash, Chen, Yun-Chi, Sinnis, Photini, Zavala, Fidel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060173/
https://www.ncbi.nlm.nih.gov/pubmed/21445239
http://dx.doi.org/10.1371/journal.ppat.1001318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060173/
https://www.ncbi.nlm.nih.gov/pubmed/21445239
http://dx.doi.org/10.1371/journal.ppat.1001318

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