RIP3 mediates the embryonic lethality of caspase-8-deficient mice

Apoptosis and necroptosis are complementary pathways controlled by common signaling adaptors, kinases and proteases; among these, caspase-8 (Casp8) is critical for death receptor (DR)-induced apoptosis. This caspase has also been implicated in nonapoptotic pathways that regulate Fas-associated via d...

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Detalles Bibliográficos
Autores principales: Kaiser, William J., Upton, Jason W., Long, Alyssa B., Livingston-Rosanoff, Devon, Daley, Lisa P., Hakem, Razqallah, Caspary, Tamara, Mocarski, Edward S.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060292/
https://www.ncbi.nlm.nih.gov/pubmed/21368762
http://dx.doi.org/10.1038/nature09857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060292/
https://www.ncbi.nlm.nih.gov/pubmed/21368762
http://dx.doi.org/10.1038/nature09857

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