Toxicokinetics, including saturable protein binding, of 4-chloro-2-methyl phenoxyacetic acid (MCPA) in patients with acute poisoning

Human data on protein binding and dose-dependent changes in toxicokinetics for MCPA are very limited. 128 blood samples were obtained in 49 patients with acute MCPA poisoning and total and unbound concentrations of MCPA were determined. The Scatchard plot was biphasic suggesting protein binding to t...

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Detalles Bibliográficos
Autores principales: Roberts, Darren M., Dawson, Andrew H., Senarathna, Lalith, Mohamed, Fahim, Cheng, Ron, Eaglesham, Geoffrey, Buckley, Nick A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060340/
https://www.ncbi.nlm.nih.gov/pubmed/21256202
http://dx.doi.org/10.1016/j.toxlet.2011.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060340/
https://www.ncbi.nlm.nih.gov/pubmed/21256202
http://dx.doi.org/10.1016/j.toxlet.2011.01.011

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