Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment
PURPOSE: The goal of the present research was to study post-treatment changes in polypoidal choroidal vasculopathy (PCV) shown by optical coherence tomography (OCT). METHODS: The study included 12 patients with naive PCV. Photodynamic therapy and 3 consecutive intravitreal bevacizumab injections at...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Korean Ophthalmological Society
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060400/ https://www.ncbi.nlm.nih.gov/pubmed/21461221 http://dx.doi.org/10.3341/kjo.2011.25.2.98 |
_version_ | 1782200517864194048 |
---|---|
author | Chae, Ju Byung Lee, Joo Yong Yang, Sung Jae Kim, June-Gone Yoon, Young Hee |
author_facet | Chae, Ju Byung Lee, Joo Yong Yang, Sung Jae Kim, June-Gone Yoon, Young Hee |
author_sort | Chae, Ju Byung |
collection | PubMed |
description | PURPOSE: The goal of the present research was to study post-treatment changes in polypoidal choroidal vasculopathy (PCV) shown by optical coherence tomography (OCT). METHODS: The study included 12 patients with naive PCV. Photodynamic therapy and 3 consecutive intravitreal bevacizumab injections at 6-week intervals were given. Best corrected visual acuity, subretinal fluid (SRF), pigment epithelium detachment (PED), central macular thickness (CMT), and total macular volume (TMV) were measured before and after treatment as assessed by Stratus OCT3. RESULTS: After treatment, the SRF height decreased earlier than the PED height. The SRF diameter decreased with statistical significance. However, the PED diameter did not show a statistically significant improvement, persisting at pre-treatment levels. Both CMT and TMV decreased significantly after treatment. CONCLUSIONS: After PCV treatment, SRF and PED stabilized, as shown by OCT. However, the PED treatment response was both delayed and refractory compared to the SRF response. The small change in post-treatment PED diameter may suggest the possibility of PCV recurrence. |
format | Text |
id | pubmed-3060400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Ophthalmological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-30604002011-04-01 Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment Chae, Ju Byung Lee, Joo Yong Yang, Sung Jae Kim, June-Gone Yoon, Young Hee Korean J Ophthalmol Original Article PURPOSE: The goal of the present research was to study post-treatment changes in polypoidal choroidal vasculopathy (PCV) shown by optical coherence tomography (OCT). METHODS: The study included 12 patients with naive PCV. Photodynamic therapy and 3 consecutive intravitreal bevacizumab injections at 6-week intervals were given. Best corrected visual acuity, subretinal fluid (SRF), pigment epithelium detachment (PED), central macular thickness (CMT), and total macular volume (TMV) were measured before and after treatment as assessed by Stratus OCT3. RESULTS: After treatment, the SRF height decreased earlier than the PED height. The SRF diameter decreased with statistical significance. However, the PED diameter did not show a statistically significant improvement, persisting at pre-treatment levels. Both CMT and TMV decreased significantly after treatment. CONCLUSIONS: After PCV treatment, SRF and PED stabilized, as shown by OCT. However, the PED treatment response was both delayed and refractory compared to the SRF response. The small change in post-treatment PED diameter may suggest the possibility of PCV recurrence. The Korean Ophthalmological Society 2011-04 2011-03-11 /pmc/articles/PMC3060400/ /pubmed/21461221 http://dx.doi.org/10.3341/kjo.2011.25.2.98 Text en © 2011 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Chae, Ju Byung Lee, Joo Yong Yang, Sung Jae Kim, June-Gone Yoon, Young Hee Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title | Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title_full | Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title_fullStr | Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title_full_unstemmed | Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title_short | Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment |
title_sort | time-lag between subretinal fluid and pigment epithelial detachment reduction after polypoidal choroidal vasculopathy treatment |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060400/ https://www.ncbi.nlm.nih.gov/pubmed/21461221 http://dx.doi.org/10.3341/kjo.2011.25.2.98 |
work_keys_str_mv | AT chaejubyung timelagbetweensubretinalfluidandpigmentepithelialdetachmentreductionafterpolypoidalchoroidalvasculopathytreatment AT leejooyong timelagbetweensubretinalfluidandpigmentepithelialdetachmentreductionafterpolypoidalchoroidalvasculopathytreatment AT yangsungjae timelagbetweensubretinalfluidandpigmentepithelialdetachmentreductionafterpolypoidalchoroidalvasculopathytreatment AT kimjunegone timelagbetweensubretinalfluidandpigmentepithelialdetachmentreductionafterpolypoidalchoroidalvasculopathytreatment AT yoonyounghee timelagbetweensubretinalfluidandpigmentepithelialdetachmentreductionafterpolypoidalchoroidalvasculopathytreatment |