Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis

It has been 100 years since the first report of sickle haemoglobin (HbS). More than 50 years ago, it was suggested that the gene responsible for this disorder could reach high frequencies because of resistance conferred against malaria by the heterozygous carrier state. This traditional example of b...

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Detalles Bibliográficos
Autores principales: Piel, Frédéric B., Patil, Anand P., Howes, Rosalind E., Nyangiri, Oscar A., Gething, Peter W., Williams, Thomas N., Weatherall, David J., Hay, Simon I.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060623/
https://www.ncbi.nlm.nih.gov/pubmed/21045822
http://dx.doi.org/10.1038/ncomms1104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060623/
https://www.ncbi.nlm.nih.gov/pubmed/21045822
http://dx.doi.org/10.1038/ncomms1104

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