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MutS Switches Between Two Fundamentally Distinct Clamps during Mismatch Repair
Single molecule trajectory analysis has suggested DNA repair proteins may perform a 1–dimensional (1D) search on naked DNA encompassing >10,000 nucleotides. Organized cellular DNA (chromatin) presents substantial barriers to such lengthy searches. Using dynamic single molecule fluorescence resona...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060787/ https://www.ncbi.nlm.nih.gov/pubmed/21278758 http://dx.doi.org/10.1038/nsmb.2009 |