Cargando…

MutS Switches Between Two Fundamentally Distinct Clamps during Mismatch Repair

Single molecule trajectory analysis has suggested DNA repair proteins may perform a 1–dimensional (1D) search on naked DNA encompassing >10,000 nucleotides. Organized cellular DNA (chromatin) presents substantial barriers to such lengthy searches. Using dynamic single molecule fluorescence resona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeong, Cherlhyun, Cho, Won–Ki, Song, Kyung–Mi, Cook, Christopher, Yoon, Tae–Young, Ban, Changill, Fishel, Richard, Lee, Jong–Bong
Formato:	Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060787/ https://www.ncbi.nlm.nih.gov/pubmed/21278758 http://dx.doi.org/10.1038/nsmb.2009

Ejemplares similares

MutS functions as a clamp loader by positioning MutL on the DNA during mismatch repair
por: Yang, Xiao-Wen, et al.
Publicado: (2022)

Exploiting the distinctive properties of the bacterial and human MutS homolog sliding clamps on mismatched DNA
por: Britton, Brooke M., et al.
Publicado: (2022)

MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
por: Liu, Jiaquan, et al.
Publicado: (2019)

Electrochemical detection of mismatched DNA using a MutS probe
por: Cho, Minseon, et al.
Publicado: (2006)

Single-Molecule Analysis Reveals the Kinetics and Physiological Relevance of MutL-ssDNA Binding
por: Park, Jonghyun, et al.
Publicado: (2010)

Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS
por: Lebbink, Joyce H. G., et al.
Publicado: (2010)

The mismatch repair system (mutS and mutL) in Acinetobacter baylyi ADP1
por: Zhou, Hua, et al.
Publicado: (2020)

Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair
por: Elez, Marina, et al.
Publicado: (2012)

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA
por: Groothuizen, Flora S, et al.
Publicado: (2015)

Characterisation of the MutS and MutL Proteins from the Pseudomonas avellanae Mismatch Repair (MMR) System
por: Grenga, Lucia, et al.
Publicado: (2012)

Characterization of Multi-Functional Properties and Conformational Analysis of MutS2 from Thermotoga maritima MSB8
por: Jeong, Euiyoung, et al.
Publicado: (2012)

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation
por: Groothuizen, Flora S., et al.
Publicado: (2013)

Dynamics of MutS–Mismatched DNA Complexes Are Predictive of Their Repair Phenotypes
por: DeRocco, Vanessa C., et al.
Publicado: (2014)

SLX4 dampens MutSα-dependent mismatch repair
por: Guervilly, Jean-Hugues, et al.
Publicado: (2022)

Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repair
por: Ortega, Janice, et al.
Publicado: (2021)

MutSα maintains the mismatch repair capability by inhibiting PCNA unloading
por: Kawasoe, Yoshitaka, et al.
Publicado: (2016)

Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
por: Liu, Yiyong, et al.
Publicado: (2010)

Both hMutSα and hMutSß DNA Mismatch Repair Complexes Participate in 5-Fluorouracil Cytotoxicity
por: Tajima, Akihiro, et al.
Publicado: (2011)

The UvrD helicase and its modulation by the mismatch repair protein MutL
por: Matson, Steven W., et al.
Publicado: (2006)

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS
por: LeBlanc, Sharonda J, et al.
Publicado: (2018)

Genome-wide contributions of the MutSα- and MutSβ-dependent DNA mismatch repair pathways to the maintenance of genetic stability in Saccharomyces cerevisiae
por: Kadyrova, Lyudmila Y., et al.
Publicado: (2023)

Clamping down on mismatches
por: Li, Guo-Min
Publicado: (2016)

MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination
por: Arlow, Tim, et al.
Publicado: (2021)

The sliding clamp tethers the endonuclease domain of MutL to DNA
por: Pillon, Monica C., et al.
Publicado: (2015)

Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
por: Pluciennik, Anna, et al.
Publicado: (2009)

Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair
por: Plotz, Guido, et al.
Publicado: (2006)

Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS
por: Monti, Maria Chiara, et al.
Publicado: (2011)

MutSβ exceeds MutSα in dinucleotide loop repair
por: Kantelinen, J, et al.
Publicado: (2010)

HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions
por: Williams, Gregory M., et al.
Publicado: (2020)

The Presence of the DNA Repair Genes mutM, mutY, mutL, and mutS is Related to Proteome Size in Bacterial Genomes
por: Garcia-Gonzalez, Aurian, et al.
Publicado: (2012)

Role of the DNA Mismatch Repair Gene MutS4 in Driving the Evolution of Mycobacterium yongonense Type I via Homologous Recombination
por: Kim, Byoung-Jun, et al.
Publicado: (2017)

Binding of the regulatory domain of MutL to the sliding β-clamp is species specific
por: Almawi, Ahmad W, et al.
Publicado: (2019)

Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
por: Genschel, Jochen, et al.
Publicado: (2009)

Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein
por: Lakhani, Bharat, et al.
Publicado: (2017)

PCNA–MutSα-mediated binding of MutLα to replicative DNA with mismatched bases to induce apoptosis in human cells
por: Hidaka, Masumi, et al.
Publicado: (2005)

Mph1 requires mismatch repair-independent and -dependent functions of MutSα to regulate crossover formation during homologous recombination repair
por: Tay, Ye Dee, et al.
Publicado: (2010)

Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2017)

Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex
por: Kim, Yoori, et al.
Publicado: (2019)

The mismatch repair endonuclease MutLα tethers duplex regions of DNA together and relieves DNA torsional tension
por: Witte, Scott J, et al.
Publicado: (2023)

8-Oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSα
por: Macpherson, Peter, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_fpc5dvpqgkle3as6f7et4tmdcr