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Enhancement Effects of Martentoxin on Glioma BK Channel and BK Channel (α+β1) Subtypes

BACKGROUND: BK channels are usually activated by membrane depolarization and cytoplasmic Ca(2+). Especially,the activity of BK channel (α+β4) can be modulated by martentoxin, a 37 residues peptide, with Ca(2+)-dependent manner. gBK channel (glioma BK channel) and BK channel (α+β1) possessed higher C...

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Detalles Bibliográficos
Autores principales: Tao, Jie, Shi, Jian, Yan, Li, Chen, Ying, Duan, Yan Hong, Ye, Pin, Feng, Qi, Zhang, Jian Wei, Shu, Xue Qin, Ji, Yong Hua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060806/
https://www.ncbi.nlm.nih.gov/pubmed/21445248
http://dx.doi.org/10.1371/journal.pone.0015896