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Putative EPHX1 Enzyme Activity Is Related with Risk of Lung and Upper Aerodigestive Tract Cancers: A Comprehensive Meta-Analysis

BACKGROUND: EPHX1 is a key enzyme in metabolizing some exogenous carcinogens such as products of cigarette-smoking. Two functional polymorphisms in the EPHX1 gene, Tyr113His and His139Arg can alter the enzyme activity, suggesting their possible association with carcinogenesis risk, particularly of s...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Hu, Zheng, Qu, Xinshun, Zhu, Jiadong, Li, Lin, Ring, Brian Z., Su, Li
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060809/
https://www.ncbi.nlm.nih.gov/pubmed/21445251
http://dx.doi.org/10.1371/journal.pone.0014749