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Identification of Local Conformational Similarity in Structurally Variable Regions of Homologous Proteins Using Protein Blocks
Structure comparison tools can be used to align related protein structures to identify structurally conserved and variable regions and to infer functional and evolutionary relationships. While the conserved regions often superimpose well, the variable regions appear non superimposable. Differences i...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060819/ https://www.ncbi.nlm.nih.gov/pubmed/21445259 http://dx.doi.org/10.1371/journal.pone.0017826 |