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Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein

Bacterial cell walls contain peptidoglycan, an essential polymer made by enzymes in the Mur pathway. These proteins are specific to bacteria, which make them targets for drug discovery. MurC, MurD, MurE and MurF catalyze the synthesis of the peptidoglycan precursor UDP-N-acetylmuramoyl-L-alanyl-γ-D-...

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Detalles Bibliográficos
Autores principales: Das, Debanu, Hervé, Mireille, Feuerhelm, Julie, Farr, Carol L., Chiu, Hsiu-Ju, Elsliger, Marc-André, Knuth, Mark W., Klock, Heath E., Miller, Mitchell D., Godzik, Adam, Lesley, Scott A., Deacon, Ashley M., Mengin-Lecreulx, Dominique, Wilson, Ian A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060825/
https://www.ncbi.nlm.nih.gov/pubmed/21445265
http://dx.doi.org/10.1371/journal.pone.0017624