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Proteomic Identification of Protein Targets for 15-Deoxy-Δ(12,14)-Prostaglandin J(2) in Neuronal Plasma Membrane

15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) is one of factors contributed to the neurotoxicity of amyloid β (Aβ), a causative protein of Alzheimer's disease. Type 2 receptor for prostaglandin D(2) (DP2) and peroxysome-proliferator activated receptorγ (PPARγ) are identified as the membrane...

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Detalles Bibliográficos
Autores principales: Yamamoto, Yasuhiro, Takase, Kenkichi, Kishino, Junji, Fujita, Megumi, Okamura, Noboru, Sakaeda, Toshiyuki, Fujimoto, Masafumi, Yagami, Tatsurou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060826/
https://www.ncbi.nlm.nih.gov/pubmed/21445266
http://dx.doi.org/10.1371/journal.pone.0017552