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Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure

BACKGROUND: Artemisinin-combination therapy is a highly effective treatment for uncomplicated falciparum malaria but parasite recrudescence has been commonly reported following artemisinin (ART) monotherapy. The dormancy recovery hypothesis has been proposed to explain this phenomenon, which is diff...

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Detalles Bibliográficos
Autores principales: Codd, Andrea, Teuscher, Franka, Kyle, Dennis E, Cheng, Qin, Gatton, Michelle L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060839/
https://www.ncbi.nlm.nih.gov/pubmed/21385409
http://dx.doi.org/10.1186/1475-2875-10-56