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Small RNA profiling of Dengue virus-mosquito interactions implicates the PIWI RNA pathway in anti-viral defense

BACKGROUND: Small RNA (sRNA) regulatory pathways (SRRPs) are important to anti-viral defence in mosquitoes. To identify critical features of the virus infection process in Dengue serotype 2 (DENV2)-infected Ae. aegypti, we deep-sequenced small non-coding RNAs. Triplicate biological replicates were u...

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Detalles Bibliográficos
Autores principales: Hess, Ann M, Prasad, Abhishek N, Ptitsyn, Andrey, Ebel, Gregory D, Olson, Ken E, Barbacioru, Catalin, Monighetti, Cinna, Campbell, Corey L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060848/
https://www.ncbi.nlm.nih.gov/pubmed/21356105
http://dx.doi.org/10.1186/1471-2180-11-45