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Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of β-receptor affinity in murine models of asthma

BACKGROUND: Inhaled short acting β2-agonists (SABA), e.g. albuterol, are used for quick reversal of bronchoconstriction in asthmatics. While SABA are not recommended for maintenance therapy, it is not uncommon to find patients who frequently use SABA over a long period of time and there is a suspici...

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Detalles Bibliográficos
Autores principales: Lundblad, Lennart KA, Rinaldi, Lisa M, Poynter, Matthew E, Riesenfeld, Erik P, Wu, Min, Aimi, Steven, Barone, Leesa M, Bates, Jason HT, Irvin, Charles G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060863/
https://www.ncbi.nlm.nih.gov/pubmed/21385381
http://dx.doi.org/10.1186/1465-9921-12-27