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Acute Endotoxin-Induced Thymic Atrophy Is Characterized By Intrathymic Inflammatory and Wound Healing Responses

BACKGROUND: Productive thymopoiesis is essential for a robust and healthy immune system. Thymus unfortunately is acutely sensitive to stress resulting in involution and decreased T cell production. Thymic involution is a complication of many clinical settings, including infection, malnutrition, star...

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Detalles Bibliográficos
Autores principales: Billard, Matthew J., Gruver, Amanda L., Sempowski, Gregory D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060875/
https://www.ncbi.nlm.nih.gov/pubmed/21437240
http://dx.doi.org/10.1371/journal.pone.0017940