FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways

Fibroblast growth factor 19 (FGF19) is a hormone-like protein that regulates carbohydrate, lipid and bile acid metabolism. At supra-physiological doses, FGF19 also increases hepatocyte proliferation and induces hepatocellular carcinogenesis in mice. Much of FGF19 activity is attributed to the activa...

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Detalles Bibliográficos
Autores principales: Wu, Ai-Luen, Coulter, Sally, Liddle, Christopher, Wong, Anne, Eastham-Anderson, Jeffrey, French, Dorothy M., Peterson, Andrew S., Sonoda, Junichiro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060878/
https://www.ncbi.nlm.nih.gov/pubmed/21437243
http://dx.doi.org/10.1371/journal.pone.0017868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060878/
https://www.ncbi.nlm.nih.gov/pubmed/21437243
http://dx.doi.org/10.1371/journal.pone.0017868

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