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FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways
Fibroblast growth factor 19 (FGF19) is a hormone-like protein that regulates carbohydrate, lipid and bile acid metabolism. At supra-physiological doses, FGF19 also increases hepatocyte proliferation and induces hepatocellular carcinogenesis in mice. Much of FGF19 activity is attributed to the activa...
Autores principales: | Wu, Ai-Luen, Coulter, Sally, Liddle, Christopher, Wong, Anne, Eastham-Anderson, Jeffrey, French, Dorothy M., Peterson, Andrew S., Sonoda, Junichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060878/ https://www.ncbi.nlm.nih.gov/pubmed/21437243 http://dx.doi.org/10.1371/journal.pone.0017868 |
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