In Vivo Imaging Reveals Distinct Inflammatory Activity of CNS Microglia versus PNS Macrophages in a Mouse Model for ALS

Mutations in the enzyme superoxide dismutase-1 (SOD1) cause hereditary variants of the fatal motor neuronal disease Amyotrophic lateral sclerosis (ALS). Pathophysiology of the disease is non-cell-autonomous: neurotoxicity is derived not only from mutant motor neurons but also from mutant neighbourin...

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Detalles Bibliográficos
Autores principales: Dibaj, Payam, Steffens, Heinz, Zschüntzsch, Jana, Nadrigny, Fabien, Schomburg, Eike D., Kirchhoff, Frank, Neusch, Clemens
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060882/
https://www.ncbi.nlm.nih.gov/pubmed/21437247
http://dx.doi.org/10.1371/journal.pone.0017910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060882/
https://www.ncbi.nlm.nih.gov/pubmed/21437247
http://dx.doi.org/10.1371/journal.pone.0017910

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