The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells

BACKGROUND: Notch and Wnt pathways are key regulators of intestinal homeostasis and alterations in these pathways may lead to the development of colorectal cancer (CRC). In CRC the Apc/β-catenin genes in the Wnt signaling pathway are frequently mutated and active Notch signaling contributes to tumor...

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Detalles Bibliográficos
Autores principales: Ungerbäck, Jonas, Elander, Nils, Grünberg, John, Sigvardsson, Mikael, Söderkvist, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060910/
https://www.ncbi.nlm.nih.gov/pubmed/21437251
http://dx.doi.org/10.1371/journal.pone.0017957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060910/
https://www.ncbi.nlm.nih.gov/pubmed/21437251
http://dx.doi.org/10.1371/journal.pone.0017957

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