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The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells
BACKGROUND: Notch and Wnt pathways are key regulators of intestinal homeostasis and alterations in these pathways may lead to the development of colorectal cancer (CRC). In CRC the Apc/β-catenin genes in the Wnt signaling pathway are frequently mutated and active Notch signaling contributes to tumor...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060910/ https://www.ncbi.nlm.nih.gov/pubmed/21437251 http://dx.doi.org/10.1371/journal.pone.0017957 |