The Relationship between the Val158Met Catechol-o-Methyltransferase (COMT) Polymorphism and Irritable Bowel Syndrome

BACKGROUND: The catechol-O-methyltransferase (COMT) enzyme has a key function in the degradation of catecholamines and a functional polymorphism is val158met. The val/val genotype results in a three to fourfold higher enzymatic activity compared with the met/met genotype, with the val/met genotype e...

Descripción completa

Detalles Bibliográficos
Autores principales: Karling, Pontus, Danielsson, Åke, Wikgren, Mikael, Söderström, Ingegerd, Del-Favero, Jurgen, Adolfsson, Rolf, Norrback, Karl-Fredrik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060919/
https://www.ncbi.nlm.nih.gov/pubmed/21437260
http://dx.doi.org/10.1371/journal.pone.0018035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060919/
https://www.ncbi.nlm.nih.gov/pubmed/21437260
http://dx.doi.org/10.1371/journal.pone.0018035

Ejemplares similares