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Screening of Random Peptide Library of Hemagglutinin from Pandemic 2009 A(H1N1) Influenza Virus Reveals Unexpected Antigenically Important Regions

The antigenic structure of the membrane protein hemagglutinin (HA) from the 2009 A(H1N1) influenza virus was dissected with a high-throughput screening method using complex antisera. The approach involves generating yeast cell libraries displaying a pool of random peptides of controllable lengths on...

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Detalles Bibliográficos
Autores principales: Xu, Wanghui, Han, Lu, Lin, Zhanglin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060926/
https://www.ncbi.nlm.nih.gov/pubmed/21437206
http://dx.doi.org/10.1371/journal.pone.0018016