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Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing

The conserved pre-mRNA splicing factor SF1 is implicated in 3′ splice site recognition by binding directly to the intron branch site. However, because SF1 is not essential for constitutive splicing, its role in pre-mRNA processing has remained mysterious. Here, we used crosslinking and immunoprecipi...

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Detalles Bibliográficos
Autores principales: Corioni, Margherita, Antih, Nicolas, Tanackovic, Goranka, Zavolan, Mihaela, Krämer, Angela
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061054/
https://www.ncbi.nlm.nih.gov/pubmed/21062807
http://dx.doi.org/10.1093/nar/gkq1042