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A simple method using Pyrosequencing(TM) to identify de novo SNPs in pooled DNA samples
A practical way to reduce the cost of surveying single-nucleotide polymorphism (SNP) in a large number of individuals is to measure the allele frequencies in pooled DNA samples. Pyrosequencing(TM) has been frequently used for this application because signals generated by this approach are proportion...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061071/ https://www.ncbi.nlm.nih.gov/pubmed/21131285 http://dx.doi.org/10.1093/nar/gkq1249 |