Directed adenovirus evolution using engineered mutator viral polymerases

Adenoviruses (Ads) are the most frequently used viruses for oncolytic and gene therapy purposes. Most Ad-based vectors have been generated through rational design. Although this led to significant vector improvements, it is often hampered by an insufficient understanding of Ad’s intricate functions...

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Detalles Bibliográficos
Autores principales: Uil, Taco G., Vellinga, Jort, de Vrij, Jeroen, van den Hengel, Sanne K., Rabelink, Martijn J. W. E., Cramer, Steve J., Eekels, Julia J. M., Ariyurek, Yavuz, van Galen, Michiel, Hoeben, Rob C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061072/
https://www.ncbi.nlm.nih.gov/pubmed/21138963
http://dx.doi.org/10.1093/nar/gkq1258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061072/
https://www.ncbi.nlm.nih.gov/pubmed/21138963
http://dx.doi.org/10.1093/nar/gkq1258

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