Cargando…

A general and efficient approach for the construction of RNA oligonucleotides containing a 5′-phosphorothiolate linkage

Oligoribonucleotides containing a 5′-phosphorothiolate linkage have provided effective tools to study the mechanisms of RNA catalysis, allowing resolution of kinetic ambiguity associated with mechanistic dissection and providing a strategy to establish linkage between catalysis and specific function...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Nan-Sheng, Frederiksen, John K., Koo, Selene C., Lu, Jun, Wilson, Timothy J., Lilley, David M. J., Piccirilli, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061073/
https://www.ncbi.nlm.nih.gov/pubmed/21148150
http://dx.doi.org/10.1093/nar/gkq1265