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Sensitive and accurate identification of protein–DNA binding events in ChIP-chip assays using higher order derivative analysis

Immuno-precipitation of protein–DNA complexes followed by microarray hybridization is a powerful and cost-effective technology for discovering protein–DNA binding events at the genome scale. It is still an unresolved challenge to comprehensively, accurately and sensitively extract binding event info...

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Detalles Bibliográficos
Autores principales: Barrett, Christian L., Cho, Byung-Kwan, Palsson, Bernhard O.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061075/
https://www.ncbi.nlm.nih.gov/pubmed/21051353
http://dx.doi.org/10.1093/nar/gkq848