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Sensitive and accurate identification of protein–DNA binding events in ChIP-chip assays using higher order derivative analysis
Immuno-precipitation of protein–DNA complexes followed by microarray hybridization is a powerful and cost-effective technology for discovering protein–DNA binding events at the genome scale. It is still an unresolved challenge to comprehensively, accurately and sensitively extract binding event info...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061075/ https://www.ncbi.nlm.nih.gov/pubmed/21051353 http://dx.doi.org/10.1093/nar/gkq848 |