A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations

The F-box DNA helicase Fbh1 constrains homologous recombination in vegetative cells, most likely through an ability to displace the Rad51 recombinase from DNA. Here, we provide the first evidence that Fbh1 also serves a vital meiotic role in fission yeast to promote normal chromosome segregation. In...

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Detalles Bibliográficos
Autores principales: Sun, Weili, Lorenz, Alexander, Osman, Fekret, Whitby, Matthew C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061084/
https://www.ncbi.nlm.nih.gov/pubmed/21149262
http://dx.doi.org/10.1093/nar/gkq977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061084/
https://www.ncbi.nlm.nih.gov/pubmed/21149262
http://dx.doi.org/10.1093/nar/gkq977

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