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Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles

BACKGROUND: Polybutylcyanoacrylate (PBCA) nanoparticles coated with polysorbate-80 have been extensively proposed for delivering drugs into the animal brain and have shown great potential for therapeutic applications. In this study, we made an attempt to deliver the chemotherapeutic drug, temozolomi...

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Detalles Bibliográficos
Autores principales: Tian, Xin-Hua, Lin, Xiao-Ning, Wei, Feng, Feng, Wei, Huang, Zhi-Chun, Wang, Peng, Ren, Lei, Diao, Yi
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061435/
https://www.ncbi.nlm.nih.gov/pubmed/21445277
http://dx.doi.org/10.2147/IJN.S16570