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Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations
BACKGROUND: The objective of this study is to identify the critical formulation parameters controlling distribution and function for the rectal administration of microbicides in humans. Four placebo formulations were designed with a wide range of hydrophilic characteristics (aqueous to lipid) and rh...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061893/ https://www.ncbi.nlm.nih.gov/pubmed/21385339 http://dx.doi.org/10.1186/1742-6405-8-12 |