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Tim-3 expression on peripheral T cell subsets correlates with disease progression in hepatitis B infection

BACKGROUND AND OBJECTIVE: T-cell immunoglobulin domain and mucin domain-containing molecule-3 (Tim-3) represents a novel mechanism of T-cell dysfunction in chronic viral diseases. However, the role of Tim-3 in the pathogenesis of chronic hepatitis B (CHB) is not well understood. We investigated Tim-...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Shi, Yu, Li, Jie, Chen, Feng, Chen, Zhi, Zheng, Min
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061941/
https://www.ncbi.nlm.nih.gov/pubmed/21392402
http://dx.doi.org/10.1186/1743-422X-8-113