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Location of Intra- and Extracellular M. tuberculosis Populations in Lungs of Mice and Guinea Pigs during Disease Progression and after Drug Treatment

The lengthy treatment regimen for tuberculosis is necessary to eradicate a small sub-population of M. tuberculosis that persists in certain host locations under drug pressure. Limited information is available on persisting bacilli and their location within the lung during disease progression and aft...

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Detalles Bibliográficos
Autores principales: Hoff, Donald R., Ryan, Gavin J., Driver, Emily R., Ssemakulu, Cornelius C., De Groote, Mary A., Basaraba, Randall J., Lenaerts, Anne J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061964/
https://www.ncbi.nlm.nih.gov/pubmed/21445321
http://dx.doi.org/10.1371/journal.pone.0017550