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PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1

Recent publications suggest that the Parkinson's disease- (PD-) related PINK1/Parkin pathway promotes elimination of dysfunctional mitochondria by autophagy. We used tandem affinity purification (TAP), SDS-PAGE, and mass spectrometry as a first step towards identification of possible substrates...

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Detalles Bibliográficos
Autores principales: Rakovic, Aleksandar, Grünewald, Anne, Voges, Lisa, Hofmann, Sarah, Orolicki, Slobodanka, Lohmann, Katja, Klein, Christine
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062077/
https://www.ncbi.nlm.nih.gov/pubmed/21437181
http://dx.doi.org/10.4061/2011/153979