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Impact of KRAS Mutations on Management of Colorectal Carcinoma

The epidermal growth factor receptor (EGFR) pathway is a therapeutic target in the management of colorectal cancer (CRC). EGFR antagonists are active in this disease; however, only a subset of patients respond to such therapy. A Kirsten ras sarcoma viral oncogene (KRAS) wild-type (WT) status of the...

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Detalles Bibliográficos
Autores principales: Sullivan, Kevin M., Kozuch, Peter S.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062096/
https://www.ncbi.nlm.nih.gov/pubmed/21437184
http://dx.doi.org/10.4061/2011/219309