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Phosphorylation of Annexin A1 by TRPM7 Kinase: A Switch Regulating the Induction of an α-Helix

[Image: see text] TRPM7 is an unusual bifunctional protein consisting of an α-kinase domain fused to a TRP ion channel. Previously, we have identified annexin A1 as a substrate for TRPM7 kinase and found that TRPM7 phosphorylates annexin A1 at Ser5 within the N-terminal α-helix. Annexin A1 is a Ca(2...

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Detalles Bibliográficos
Autores principales: Dorovkov, Maxim V., Kostyukova, Alla S., Ryazanov, Alexey G.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062375/
https://www.ncbi.nlm.nih.gov/pubmed/21280599
http://dx.doi.org/10.1021/bi101963h