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A Network-Based Multi-Target Computational Estimation Scheme for Anticoagulant Activities of Compounds

BACKGROUND: Traditional virtual screening method pays more attention on predicted binding affinity between drug molecule and target related to a certain disease instead of phenotypic data of drug molecule against disease system, as is often less effective on discovery of the drug which is used to tr...

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Detalles Bibliográficos
Autores principales: Li, Qian, Li, Xudong, Li, Canghai, Chen, Lirong, Song, Jun, Tang, Yalin, Xu, Xiaojie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062543/
https://www.ncbi.nlm.nih.gov/pubmed/21445339
http://dx.doi.org/10.1371/journal.pone.0014774