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Direct Gene Transfer with IP-10 Mutant Ameliorates Mouse CVB3-Induced Myocarditis by Blunting Th1 Immune Responses

BACKGROUND: Myocarditis is an inflammation of the myocardium that often follows the enterovirus infections, with coxsackievirus B3 (CVB3) being the most dominant etiologic agent. We and other groups previously reported that chemokine IP-10 was significantly induced in the heart tissue of CVB3-infect...

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Detalles Bibliográficos
Autores principales: Yue, Yan, Gui, Jun, Ai, Wenqing, Xu, Wei, Xiong, Sidong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062568/
https://www.ncbi.nlm.nih.gov/pubmed/21445362
http://dx.doi.org/10.1371/journal.pone.0018186