How the biotin–streptavidin interaction was made even stronger: investigation via crystallography and a chimaeric tetramer

The interaction between SA (streptavidin) and biotin is one of the strongest non-covalent interactions in Nature. SA is a widely used tool and a paradigm for protein–ligand interactions. We previously developed a SA mutant, termed Tr (traptavidin), possessing a 10-fold lower off-rate for biotin, wit...

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Detalles Bibliográficos
Autores principales: Chivers, Claire E., Koner, Apurba L., Lowe, Edward D., Howarth, Mark
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062853/
https://www.ncbi.nlm.nih.gov/pubmed/21241253
http://dx.doi.org/10.1042/BJ20101593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062853/
https://www.ncbi.nlm.nih.gov/pubmed/21241253
http://dx.doi.org/10.1042/BJ20101593

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