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WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line

The Wilms' tumour suppressor WT1 (Wilms' tumour 1) is a transcriptional regulator that plays a central role in organogenesis, and is mutated or aberrantly expressed in several childhood and adult malignancies. We previously identified BASP1 (brain acid-soluble protein 1) as a WT1 cofactor...

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Detalles Bibliográficos
Autores principales: Goodfellow, Sarah J., Rebello, Michelle R., Toska, Eneda, Zeef, Leo A. H., Rudd, Sean G., Medler, Kathryn F., Roberts, Stefan G. E.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062854/
https://www.ncbi.nlm.nih.gov/pubmed/21269271
http://dx.doi.org/10.1042/BJ20101734