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WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line
The Wilms' tumour suppressor WT1 (Wilms' tumour 1) is a transcriptional regulator that plays a central role in organogenesis, and is mutated or aberrantly expressed in several childhood and adult malignancies. We previously identified BASP1 (brain acid-soluble protein 1) as a WT1 cofactor...
Autores principales: | Goodfellow, Sarah J., Rebello, Michelle R., Toska, Eneda, Zeef, Leo A. H., Rudd, Sean G., Medler, Kathryn F., Roberts, Stefan G. E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062854/ https://www.ncbi.nlm.nih.gov/pubmed/21269271 http://dx.doi.org/10.1042/BJ20101734 |
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