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One Function—Multiple Mechanisms: The Manifold Activities of p53 as a Transcriptional Repressor
Maintenance of genome integrity is a dynamic process involving complex regulation systems. Defects in one or more of these pathways could result in cancer. The most important tumor-suppressor is the transcription factor p53, and its functional inactivation is frequently observed in many tumor types....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062963/ https://www.ncbi.nlm.nih.gov/pubmed/21436991 http://dx.doi.org/10.1155/2011/464916 |