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A two step synthesis of a key unit B precursor of cryptophycins by asymmetric hydrogenation
A novel highly enantioselective two step access to a unit B precursor of cryptophycins in good yields from commercially available starting materials has been developed. The key step is an asymmetric hydrogenation using the commercially available [(COD)Rh-(R,R)-Et-DuPhos]BF(4) catalyst. The synthetic...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063055/ https://www.ncbi.nlm.nih.gov/pubmed/21448253 http://dx.doi.org/10.3762/bjoc.7.32 |