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The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment

Astrin is a mitotic spindle–associated protein required for the correct alignment of all chromosomes at the metaphase plate. Astrin depletion delays chromosome alignment and causes the loss of normal spindle architecture and sister chromatid cohesion before anaphase onset. Here we describe an astrin...

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Detalles Bibliográficos
Autores principales: Dunsch, Anja K., Linnane, Emily, Barr, Francis A., Gruneberg, Ulrike
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063133/
https://www.ncbi.nlm.nih.gov/pubmed/21402792
http://dx.doi.org/10.1083/jcb.201008023