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PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans

Germ granules are germ lineage–specific ribonucleoprotein (RNP) complexes, but how they are assembled and specifically segregated to germ lineage cells remains unclear. Here, we show that the PGL proteins PGL-1 and PGL-3 serve as the scaffold for germ granule formation in Caenorhabditis elegans. Usi...

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Detalles Bibliográficos
Autores principales: Hanazawa, Momoyo, Yonetani, Masafumi, Sugimoto, Asako
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063142/
https://www.ncbi.nlm.nih.gov/pubmed/21402787
http://dx.doi.org/10.1083/jcb.201010106