Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

The understanding of integral membrane protein (IMP) structure and function is hampered by the difficulty of handling these proteins. Aqueous solubilization, necessary for many types of biophysical analysis, generally requires a detergent to shield the large lipophilic surfaces displayed by native I...

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Detalles Bibliográficos
Autores principales: Chae, Pil Seok, Rasmussen, Søren G. F., Rana, Rohini, Gotfryd, Kamil, Chandra, Richa, Goren, Michael A., Kruse, Andrew C., Nurva, Shailika, Loland, Claus J., Pierre, Yves, Drew, David, Popot, Jean-Luc, Picot, Daniel, Fox, Brian G., Guan, Lan, Gether, Ulrik, Byrne, Bernadette, Kobilka, Brian, Gellman, Samuel H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063152/
https://www.ncbi.nlm.nih.gov/pubmed/21037590
http://dx.doi.org/10.1038/nmeth.1526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063152/
https://www.ncbi.nlm.nih.gov/pubmed/21037590
http://dx.doi.org/10.1038/nmeth.1526

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