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Cytolytic T lymphocytes from HLA-B8(+ )donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus

Epstein Barr virus (EBV) is a lymphotrophic γ-herpesvirus that infects more than 90% of the adult human population. It transforms B cells in vitro and is associated with lymphomas in vivo. In most EBV carriers the emergence of these malignancies, however, is prevented by T cell mediated immune contr...

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Detalles Bibliográficos
Autores principales: Tsang, Ming L, Münz, Christian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063197/
https://www.ncbi.nlm.nih.gov/pubmed/21429247
http://dx.doi.org/10.1186/2042-4280-2-4