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Cytolytic T lymphocytes from HLA-B8(+ )donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus
Epstein Barr virus (EBV) is a lymphotrophic γ-herpesvirus that infects more than 90% of the adult human population. It transforms B cells in vitro and is associated with lymphomas in vivo. In most EBV carriers the emergence of these malignancies, however, is prevented by T cell mediated immune contr...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063197/ https://www.ncbi.nlm.nih.gov/pubmed/21429247 http://dx.doi.org/10.1186/2042-4280-2-4 |