EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: A potential mechanism of EGFR-driven antagonism of apoptosis

BACKGROUND: Epidermal growth factor receptor (EGFR) plays an essential role in normal development, tumorigenesis and malignant biology of human cancers, and is known to undergo intracellular trafficking to subcellular organelles. Although several studies have shown that EGFR translocates into the mi...

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Detalles Bibliográficos
Autores principales: Cao, Xinyu, Zhu, Hu, Ali-Osman, Francis, Lo, Hui-Wen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063231/
https://www.ncbi.nlm.nih.gov/pubmed/21388543
http://dx.doi.org/10.1186/1476-4598-10-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063231/
https://www.ncbi.nlm.nih.gov/pubmed/21388543
http://dx.doi.org/10.1186/1476-4598-10-26

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