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Corticotropin Releasing Factor-Induced CREB Activation in Striatal Neurons Occurs via a Novel Gβγ Signaling Pathway

The peptide corticotropin-releasing factor (CRF) was initially identified as a critical component of the stress response. CRF exerts its cellular effects by binding to one of two cognate G-protein coupled receptors (GPCRs), CRF receptor 1 (CRFR1) or 2 (CRFR2). While these GPCRs were originally chara...

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Detalles Bibliográficos
Autores principales: Stern, Christopher M., Luoma, Jessie I., Meitzen, John, Mermelstein, Paul G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063246/
https://www.ncbi.nlm.nih.gov/pubmed/21448293
http://dx.doi.org/10.1371/journal.pone.0018114