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Corticotropin Releasing Factor-Induced CREB Activation in Striatal Neurons Occurs via a Novel Gβγ Signaling Pathway
The peptide corticotropin-releasing factor (CRF) was initially identified as a critical component of the stress response. CRF exerts its cellular effects by binding to one of two cognate G-protein coupled receptors (GPCRs), CRF receptor 1 (CRFR1) or 2 (CRFR2). While these GPCRs were originally chara...
Autores principales: | Stern, Christopher M., Luoma, Jessie I., Meitzen, John, Mermelstein, Paul G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063246/ https://www.ncbi.nlm.nih.gov/pubmed/21448293 http://dx.doi.org/10.1371/journal.pone.0018114 |
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